Some reactions could be localized and limited.

If the drop in blood pressure is sudden and drastic, it can lead to unconsciousness, even cardiac arrest and death. Signs or symptoms of an allergic attack include any, some, or most of the following:Epidermis: irritation, redness, itching, swelling, blistering, weeping, crusting, rash, eruptions, or hives Lung area: wheezing, tightness, cough, or shortness of breathHead: swelling or bumps on the facial skin and throat, eyelids, lips, tongue, or throat, hoarseness of voice, headacheNose: stuffy nose, runny nose , sneezingEyes: crimson , itchy, swollen, or watery or swelling of the area around the face and eyesStomach: pain, nausea, vomiting, diarrhea, or bloody diarrheaOther: fatigue, sore throat..The most common adverse event was diarrhea, that was mild or moderate in all cases. Grade three or four 4 neutropenia happened in six patients, most of whom were receiving ribavirin and peginterferon as well as the two direct-acting antiviral brokers. No grade 3 or 4 4 events related to hemoglobin platelet or levels counts were observed. Transient elevations of alanine aminotransferase amounts were observed in six patients; these elevations were not associated with clinically significant increases in bilirubin level.