Oxidative stress is regarded as the main culprit.

‘This acquiring contrasts with the generally held belief that the functional integrity of the endothelium is certainly compromised as we age. Our study suggests that blood vessels adapt through the aging process to modify ROS and minimize cell loss of life when put through an abrupt increase in oxidative stress. This adaptation helps to make sure that the arteries of old individuals can still do their jobs.’ ‘Although more research are needed to identify the system where the endothelium adapts to advanced age group, our study provides evidence that the natural tendency of the body is to adapt to oxidative stress during healthy aging,’ Segal said..– Denver, CO 8. Gordon H. Sasaki, M.D., F.A.C.S. – Pasadena CA 9. Scot Bradley Glasberg, M.D. – New York, NY 10. S. Randolph Waldman, M.D. – Lexington, KY Top 10 10 Dermatologists 2013 1. Macrene Alexiades-Armenakas, M.D. PhD. FAAD PC – NY, NY 2. Ronald L. Moy, M.D. – Beverly Hills, CA 3. Doris Day, M.D., FAAD, M.A. – NY, NY 4. David J.Goldberg, M.D. – NY, NY 5. Neil Sadick, MD, FAAD, FAACS, FACP FACPh – NY, NY 6. Ava Shamban, M.D. – Beverly Hills, CA 7. Tag G. Rubin, M.D. – Beverly Hills, CA 8. Lisa Benest, M.D. – Burbank, CA 9. Debra Jaliman, M.D. – NY, NY 10. Jeanine B. Downie, M.D. – Montclair, NJ Top 10 Aesthetic Companies 2013 1. Biophora 2. Custom made Skin Care DRx 4. Mybody 6. Angel Marino Exquisite Beauty 7. Vitality Institute Medical Items 9. SkinPhD, Inc. 10. Ameriderm Med Top Dental professional 2013 William Dorfman, D.D.S.